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Anthony Brown Lab

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Axonal transport and the cytoskeleton of nerve cells

Brown Lab Personnel

We are cell biologists in the Department of Neuroscience at Ohio State University. We study the cytoskeleton of nerve cells and the mechanism of axonal transport.

Our main focus is the biology neurofilaments in health and disease. We use a broad range of cellular and molecular techniques to study the transport and assembly dynamics of neurofilaments in nerve cells.

Our core expertise is in light and electron microscopy, live-cell fluorescence imaging, protein biochemistry and nerve cell culture.



EMBO workshop on Emerging Concepts of the Neuronal Cytoskeleton

Puerto Varas, Chile, March 22-26, 2015. Organized by Christian Gonzalez-Billault and Anthony Brown. Click here for more information. Read more news

Severing and annealing of neurofilaments in neurons

Live-cell imaging studies reveal evidence for dynamic regulation of neurofilament length in neurons by severing and end-to-end annealing mechanisms (Uchida et al, 2013). Read more news